2-Chloromandelic acid, known as o-chloromandelic acid, is a key pharmaceutical intermediate with the chemical formula C8H7ClO3 and a molar mass of 186.59 g/mol. It appears as white to yellowish crystals with a melting point of 90-93°C and a boiling point of 266.91°C. This compound is essential in the synthesis of clopidogrel, a drug preventing blood clots, and is used in organic chemistry to introduce the 2-chlorophenyl group into molecules. Handling 2-chloromandelic acid requires caution due to its corrosive nature, necessitating protective gear to prevent irritation and strict waste disposal to avoid environmental harm. Its role in drug production, especially clopidogrel, underscores its significance in the pharmaceutical industry, balancing its utility with safety considerations for responsible use.
N,N'-Dicyclohexylcarbodiimide (DCC), with the CAS number 538-75-0, is a key reagent in organic synthesis, especially in peptide synthesis. It has a molecular formula of C13H22N2 and a molar mass of 206.33 g/mol. DCC is a pale yellow liquid or white crystal with a melting point of 34-35°C and a boiling point of 122-124°C at 6mm Hg, indicating its potential volatility. DCC is insoluble in water but dissolves in organic solvents, making it a versatile agent in creating glutathione, acids, anhydrides, aldehydes, and ketones. Its role in peptide bond formation is crucial for biochemical research and pharmaceutical development. For optimal stability, DCC should be stored below +30°C. Its ability to facilitate precise reactions in peptide and nucleic acid synthesis marks its importance in advancing scientific discovery and pharmaceutical innovation.
N,N-Dimethylglycine (DMG), also known as N-Methylsarcosine, is a chemical compound with a significant role in pharmaceutical innovation. With the CAS number 1118-68-9, DMG has a molecular formula of C4H9NO2 and a molar mass of 103.12 g/mol. It appears as a white to slightly yellow solid and is best stored in a dark, sealed environment at room temperature. DMG's melting point ranges from 178-182°C, and it has a boiling point of about 193.35°C. Its flash point is 59.8°C, indicating potential volatility. As a pharmaceutical intermediate, DMG is used to synthesize more complex molecules and neutralize emulsifiers in Glycine-based ionic liquids. Its multifunctional nature makes it a key player in drug development, contributing to the creation of innovative medical treatments. DMG's adaptability and biological significance make it a valuable asset in advancing medical science and improving health outcomes.