2-(4-Chlorobenzoyl) Benzoic Acid, also known by its synonyms 2-Carboxy-4-chlorobenzophenone and CBB, is a key intermediate compound widely used in the pharmaceutical and dye industries. With the molecular formula C14H9ClO3 and a molecular weight of 260.67, it plays an essential role in the production of significant chemical products, such as Chlorothiazide, 2-Chloroanthraquinone, and other related compounds.
This compound exists as a white or light yellow crystalline solid with excellent stability, making it ideal for use in various industrial applications. Its versatility extends across pharmaceutical synthesis, particularly in the production of diuretic drugs like chlorthalidone, and in dye manufacturing, where it serves as a precursor for anthraquinone-based dyes.
2-(4-Chlorobenzoyl)benzoic acid (commonly known as CBB acid) is a highly reactive organic synthesis intermediate. It appears as a white to off-white crystalline powder with no obvious odor and stable chemical structure. As a key basic raw material in the pharmaceutical and dye industries, its molecular structure contains both benzoyl and carboxyl functional groups, endowing the product with excellent reaction adaptability. It can be prepared through multiple synthetic routes, with high purity and low impurity content, meeting the stringent requirements of high-end chemical production. The product has a CAS number of 85-56-3 and a customs code of 2918300090, complying with international chemical raw material standards, and is one of the indispensable core intermediates in industrial production.
Density reaches 1.357 g/cm³, melting point stabilizes at 149-150℃, boiling point is 470.8℃ (at 760 mmHg), and flash point is 238.5℃. It has stable chemical properties under normal temperature and pressure and is not easy to decompose
Easily soluble in common organic solvents such as benzene, ether, and ethanol. The dissolution process is fast and uniform, facilitating the preparation and mixing of subsequent reaction systems.
No special low-temperature or high-pressure storage environment is required. It only needs to be sealed and stored in a cool and dry place to maintain its chemical activity and physical properties for a long time, reducing warehousing costs.
Although it has mild irritancy, risks can be effectively avoided through standardized protection. It is not a hazardous good, resulting in lower compliance costs in subsequent transportation and use.
The mainstream preparation process has a yield of up to 91%, significantly reducing raw material loss and production costs, and is suitable for large-scale industrial production. It also supports the switching of multiple synthetic routes, adapting to the production equipment and raw material reserves of different manufacturers.
The functional groups in the molecular structure can react with various compounds, not only meeting the production needs of the two core fields of pharmaceuticals and dyes but also expanding to emerging fields such as coordination compound synthesis.
Strictly adhering to technical-grade chemical raw material production standards, the finished product has high purity and small batch-to-batch differences, providing reliable guarantee for the stability of downstream product quality.
It has strong adaptability to customs codes and relevant regulations. The policy support of 17.0% VAT rate and 9.0% tax rebate rate is conducive to import and export trade and cost control of domestic production enterprises.
As the core raw material for synthesizing the diuretic chlorthalidone, which is commonly used in the treatment of hypertension and edema. The high-purity characteristic of this product can ensure the reaction selectivity in the drug synthesis process, improving drug efficacy and safety.
It is a key precursor for the production of 2-chloroanthraquinone. As an important dye intermediate, 2-chloroanthraquinone is widely used in the synthesis of various anthraquinone dyes, suitable for coloring processes in textile, printing and other industries.
It can be used as a ligand for coordination compounds to synthesize luminescent materials with rare earth elements such as europium and terbium, having potential application value in fields such as fluorescence detection and display technology. It can also be used to synthesize special functional polymer materials, expanding to the new material field.
"We are a professional pharmaceutical enterprise producing chlorthalidone. We have been using this product as an intermediate for 3 years. Its purity is stable, and the reaction yield has always been maintained above 90%, which significantly reduces the subsequent purification cost. The supply cycle is stable, and there has never been a shortage. It is one of our core suppliers." — Purchasing Manager of a Large Pharmaceutical Enterprise
"As a dye manufacturer, we mainly use it to synthesize 2-chloroanthraquinone. This product has good solubility and strong compatibility with the reaction system. The dyes produced have strong coloring power and high color fastness, with excellent customer feedback. Moreover, the safety protection operation is convenient, and there are no obvious discomfort problems in workshop operations." — Technical Director of a Dye Chemical Enterprise
"Our company is engaged in the trade of fine chemical intermediates. This product has stable market demand, no special treatment is required during transportation, and the logistics cost is low. Customers report that it has good storage stability, and there will be no caking, deterioration and other problems even during long-term warehousing, with a high repurchase rate." — Business Manager of a Chemical Trading Company
What are the primary applications of 2-(4-Chlorobenzoyl) Benzoic Acid?
It is primarily used in pharmaceutical synthesis for producing chlorthalidone and in dye manufacturing as a precursor to anthraquinone dyes.
Is 2-(4-Chlorobenzoyl) Benzoic Acid toxic?
It has low toxicity but can cause irritation to the skin and eyes. Protective gear should be used during handling.
How should 2-(4-Chlorobenzoyl) Benzoic Acid be stored?
It should be stored in a sealed, dry environment at room temperature, away from heat and oxidizing agents.
Can 2-(4-Chlorobenzoyl) Benzoic Acid be used in industrial applications?
Yes, it is widely used in both the pharmaceutical and dye industries, with applications in organic synthesis as a catalyst and intermediate.
What precautions should be taken when handling this chemical?
Ensure proper protective equipment is worn, including gloves, goggles, and gas masks. Follow strict safety protocols to avoid exposure to irritants.
For more information and other intermediates, visit our Intermediates page.
2-(4-Chlorobenzoyl) Benzoic Acid, also known by its synonyms 2-Carboxy-4-chlorobenzophenone and CBB, is a key intermediate compound widely used in the pharmaceutical and dye industries. With the molecular formula C14H9ClO3 and a molecular weight of 260.67, it plays an essential role in the production of significant chemical products, such as Chlorothiazide, 2-Chloroanthraquinone, and other related compounds.
This compound exists as a white or light yellow crystalline solid with excellent stability, making it ideal for use in various industrial applications. Its versatility extends across pharmaceutical synthesis, particularly in the production of diuretic drugs like chlorthalidone, and in dye manufacturing, where it serves as a precursor for anthraquinone-based dyes.
2-(4-Chlorobenzoyl)benzoic acid (commonly known as CBB acid) is a highly reactive organic synthesis intermediate. It appears as a white to off-white crystalline powder with no obvious odor and stable chemical structure. As a key basic raw material in the pharmaceutical and dye industries, its molecular structure contains both benzoyl and carboxyl functional groups, endowing the product with excellent reaction adaptability. It can be prepared through multiple synthetic routes, with high purity and low impurity content, meeting the stringent requirements of high-end chemical production. The product has a CAS number of 85-56-3 and a customs code of 2918300090, complying with international chemical raw material standards, and is one of the indispensable core intermediates in industrial production.
Density reaches 1.357 g/cm³, melting point stabilizes at 149-150℃, boiling point is 470.8℃ (at 760 mmHg), and flash point is 238.5℃. It has stable chemical properties under normal temperature and pressure and is not easy to decompose
Easily soluble in common organic solvents such as benzene, ether, and ethanol. The dissolution process is fast and uniform, facilitating the preparation and mixing of subsequent reaction systems.
No special low-temperature or high-pressure storage environment is required. It only needs to be sealed and stored in a cool and dry place to maintain its chemical activity and physical properties for a long time, reducing warehousing costs.
Although it has mild irritancy, risks can be effectively avoided through standardized protection. It is not a hazardous good, resulting in lower compliance costs in subsequent transportation and use.
The mainstream preparation process has a yield of up to 91%, significantly reducing raw material loss and production costs, and is suitable for large-scale industrial production. It also supports the switching of multiple synthetic routes, adapting to the production equipment and raw material reserves of different manufacturers.
The functional groups in the molecular structure can react with various compounds, not only meeting the production needs of the two core fields of pharmaceuticals and dyes but also expanding to emerging fields such as coordination compound synthesis.
Strictly adhering to technical-grade chemical raw material production standards, the finished product has high purity and small batch-to-batch differences, providing reliable guarantee for the stability of downstream product quality.
It has strong adaptability to customs codes and relevant regulations. The policy support of 17.0% VAT rate and 9.0% tax rebate rate is conducive to import and export trade and cost control of domestic production enterprises.
As the core raw material for synthesizing the diuretic chlorthalidone, which is commonly used in the treatment of hypertension and edema. The high-purity characteristic of this product can ensure the reaction selectivity in the drug synthesis process, improving drug efficacy and safety.
It is a key precursor for the production of 2-chloroanthraquinone. As an important dye intermediate, 2-chloroanthraquinone is widely used in the synthesis of various anthraquinone dyes, suitable for coloring processes in textile, printing and other industries.
It can be used as a ligand for coordination compounds to synthesize luminescent materials with rare earth elements such as europium and terbium, having potential application value in fields such as fluorescence detection and display technology. It can also be used to synthesize special functional polymer materials, expanding to the new material field.
"We are a professional pharmaceutical enterprise producing chlorthalidone. We have been using this product as an intermediate for 3 years. Its purity is stable, and the reaction yield has always been maintained above 90%, which significantly reduces the subsequent purification cost. The supply cycle is stable, and there has never been a shortage. It is one of our core suppliers." — Purchasing Manager of a Large Pharmaceutical Enterprise
"As a dye manufacturer, we mainly use it to synthesize 2-chloroanthraquinone. This product has good solubility and strong compatibility with the reaction system. The dyes produced have strong coloring power and high color fastness, with excellent customer feedback. Moreover, the safety protection operation is convenient, and there are no obvious discomfort problems in workshop operations." — Technical Director of a Dye Chemical Enterprise
"Our company is engaged in the trade of fine chemical intermediates. This product has stable market demand, no special treatment is required during transportation, and the logistics cost is low. Customers report that it has good storage stability, and there will be no caking, deterioration and other problems even during long-term warehousing, with a high repurchase rate." — Business Manager of a Chemical Trading Company
What are the primary applications of 2-(4-Chlorobenzoyl) Benzoic Acid?
It is primarily used in pharmaceutical synthesis for producing chlorthalidone and in dye manufacturing as a precursor to anthraquinone dyes.
Is 2-(4-Chlorobenzoyl) Benzoic Acid toxic?
It has low toxicity but can cause irritation to the skin and eyes. Protective gear should be used during handling.
How should 2-(4-Chlorobenzoyl) Benzoic Acid be stored?
It should be stored in a sealed, dry environment at room temperature, away from heat and oxidizing agents.
Can 2-(4-Chlorobenzoyl) Benzoic Acid be used in industrial applications?
Yes, it is widely used in both the pharmaceutical and dye industries, with applications in organic synthesis as a catalyst and intermediate.
What precautions should be taken when handling this chemical?
Ensure proper protective equipment is worn, including gloves, goggles, and gas masks. Follow strict safety protocols to avoid exposure to irritants.
For more information and other intermediates, visit our Intermediates page.
