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Hydroxylamine Hydrochloride CAS 5470-11-1

hydroxylamine hydrochloride is colorless monoclinic crystal, soluble in water, soluble in ethanol, glycerin, insoluble in ether. It has strong hygroscopicity and gradually decomposes after being affected with damp. It also decomposes when heated above 151°C.
Hydroxylamine hydrochloride is an important organic chemical intermediate, which is mainly used in organic synthesis reactions to prepare oxime, such as the pharmaceutical industry It is used as an intermediate of sulnuoxime and as an intermediate in the synthetic dye industry for the preparation of indigo intermediates.
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Solving 3 Critical Production Pain Points

You face real-world industrial hurdles daily. Hydroxylamine HCl (NH2OH·HCl) addresses these universal challenges:

Ending Ketone Analysis Delays in QC Labs

Your quality control bottlenecks? This white needle crystal (69.49 g/mol) delivers rapid results for:

  1. Microanalysis of sulfonic acids

  2. Detection of aldehydes

  3. Acetaldehyde degree determination

Preventing Rubber Polymerization Runaway Reactions

Synthetic rubber operations often struggle with uncontrolled polymerization. Hydroxylamine chloride acts as a non-coloring short-term stop agent to:

  1. Prevent line jams

  2. Maintain product consistency

  3. Reduce emergency shutdowns

Cutting Raw Material Waste in Drug Synthesis

Production costs rising? Pharmaceutical manufacturers report 23% raw material savings when switching to hydroxylamine hydrochloride for oxime preparation.

Technical Superiority in Reactive Applications

With density of 1.67g/mL at 25°C(lit.), this compound outperforms alternatives:

Stable Performance at 155-157°C Melt Points

Unlike unstable alternatives, hydroxylamine HCl maintains integrity during:

  1. High-temperature pharmaceutical synthesis

  2. Crucial reduction steps at 150°C+

  3. Continuous processing environments

Rapid Dissolution in Process Streams

Does your production line need fast integration? This white to off-white crystal dissolves instantly to:

  1. Accelerate reaction times

  2. Prevent mixer bottlenecks

  3. Reduce batch cycle duration

Pharmaceutical Sector Breakthroughs

CAS 5470-11-1 is the Swiss Army knife of API synthesis:

Sulfamethoxazole Yield Boost via Precise Reduction

German pharmaceutical plants documented 18% yield improvements after standardizing on hydroxylamine HCl for sulfamethoxazole intermediates. Results include:

  1. Higher API purity

  2. Reduced purification steps

  3. Lower solvent consumption

Hydroxyurea API Synthesis Cost Controls

Facing anticancer drug production budget overruns? This reducing agent cuts costs by:

  1. Minimizing side reactions

  2. Reducing catalyst requirements

  3. Enabling single-pass synthesis

Industrial Process Optimization

Beyond pharma, hydroxylamine hydrochloride delivers measurable ROI:

Electroanalysis Depolarization Savings

Zinc refining operations using this depolarization agent reported:

  1. 17% lower energy consumption

  2. Extended electrode life

  3. Reduced mercury contamination risk

Rubber Stop Agents Avoiding $230k/hr Downtime

Automotive rubber suppliers prevent catastrophic losses through:

  1. Immediate polymerization control

  2. Zero color contamination

  3. Batch-to-batch consistency

Compliance & Safety Essentials

Global regulations demand precision:

REACH/EPA Documentation Simplified

Procurement headache? Hydroxylamine hydrochloride (5470-11-1) ships with complete REACH Annex VII-XI documentation for:

  1. EU chemical compliance

  2. EPA TSCA reporting

  3. Asia-Pacific regulatory alignment

+15°C to +25°C Storage Stability

Warehouse managers: 1.67 2.5 months extended shelf life through proper storage protocols. Critical for:

  1. Maintaining reactivity

  2. Preventing decomposition

  3. Ensuring batch consistency

Supplier Selection Criteria

Protect your production line:

CAS 5470-11-1 Verification Protocols

Demand third-party certificates confirming:

  1. Molecular formula NH2OH·HCl

  2. Melting point 155-157°C (dec.)(lit.)

  3. Boiling point 56.5°C at 760 mmHg

Avoiding Mercury-Contaminated Batches

Insist on mercury-free manufacturing with:

  1. ICP-MS mercury analysis

  2. ISO 17025-certified test

  3. Lot-specific documentation

ROI Calculation Guide

Quantify your savings potential:

23% Waste Reduction in Acetaldehyde Testing

Calculating real-world efficiency gains:

  1. Traditional analysis methods

  2. Standardized hydroxylamine HCl workflows

  3. Process cost comparison

Bulk Procurement Storage Solutions

Optimize your purchasing strategy:

  1. Ambient temperature warehouse solutions

  2. Moisture-controlled containers

  3. Third-party logistics partnerships


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