Papain (also known as papaya enzyme or papaya latex; English name: Papain) is a bio-enzyme preparation derived from natural papaya. With a CAS number of 9001-73-4, it has a clear molecular structure (molecular formula: C₁₉H₂₉N₇O₆; molecular weight: 451.477) and belongs to the cysteine protease family of peptidase C1.
The product mainly appears as an almost white lyophilized powder, and can also exist in the form of white to light tan amorphous powder or liquid. It possesses specific physicochemical properties: a density of approximately 1.5±0.1 g/cm³, a flash point of 29℃, a refractive index of 1.652, solubility in water (1.2mg/mL) and glycerol, and insolubility in most organic solvents such as ethanol, chloroform, and ether. With a LogP value of -1.47, it ensures stable solubility adaptability in different application scenarios.
This product is accompanied by Chinese and US versions of Material Safety Data Sheets (MSDS) to provide comprehensive guidance on safe use. Meanwhile, it is prepared using unripe fruits of Caric papaya as raw materials, through processes including latex extraction, coagulation, sedimentation, and drying. No artificially synthesized harmful ingredients are added throughout the process, balancing natural properties with industrial practicality.
As a cysteine protease, it can accurately act on protein hydrolysis reactions. It is an enzyme associated with cathepsins in the field of metabolic enzymes/proteases, showing a clear direction of action in inflammation/immunology-related research and applications. In vitro experiments have verified its adaptability in multiple industries.
Although it is relatively sensitive to temperature, pH value, and protein denaturation factors (e.g., strong acids, alkalis, organic solvents) and prone to conformational and activity changes due to external conditions, its enzymatic activity can be stably maintained through standardized storage (airtight packaging + cool and dry environment) and control of usage conditions, making it suitable for most industrial production processes.
The acute toxicity data is clear: the oral LD₅₀ in rats is ＞4g/kg, and the oral LD₅₀ in mice reaches 12500mg/kg, ensuring high safety within the scope of reasonable use. At the same time, it indicates potential hazards to the water environment, providing clear guidance for environmentally friendly use.
Using latex from unripe papaya fruits as raw materials, it is different from chemically synthesized enzyme preparations, with no residue risk. It meets the demand for "natural ingredients" in fields such as food and cosmetics, and is especially suitable for green production systems.
It combines efficient protein hydrolysis ability with mild action characteristics. It can not only meet the needs of food ingredient modification in the food industry, but also adapt to sophisticated processes in the pharmaceutical field (e.g., dental caries removal), and be used in textile fabric treatment and cosmetic ingredient preparation, with a wide cross-industry application scope.
It has targeted enzymatic activity, enabling high catalytic efficiency with low dosage, which can reduce the amount of raw materials used by enterprises. Meanwhile, as a non-hazardous good (transportation code: NONH), it has low logistics control costs, reducing the operating pressure of the entire industrial chain.
It can be used as a meat tenderizer to decompose connective tissue proteins in meat, improving meat texture. It can also be used for dairy protein modification to enhance product delicacy, or for plant protein hydrolysis to prepare easily absorbable peptide nutritional products, balancing taste optimization and nutritional upgrading.
Relying on its mild protein decomposition ability, it can assist in chemical-mechanical caries removal in dentistry (relevant studies have verified that it can reduce damage to healthy tissues in the treatment of primary tooth caries). At the same time, it plays a role in auxiliary anti-inflammatory treatment and tissue repair processes, helping to improve the safety and effectiveness of medical operations.
Utilizing its ability to decompose protein impurities on fiber surfaces, it realizes fabric softening and cleaning, reduces the usage of chemical detergents, enhances the skin-friendliness and environmental attributes of textiles, and meets the production needs of high-end fabrics.
It can be used as a mild exfoliating ingredient to accurately decompose aged cutin on the skin surface, avoiding excessive friction damage. It can also be used in hair care products to improve the protein structure on the hair surface, enhance hair toughness, and reduce hair breakage.
Papain (also known as papaya enzyme or papaya latex; English name: Papain) is a bio-enzyme preparation derived from natural papaya. With a CAS number of 9001-73-4, it has a clear molecular structure (molecular formula: C₁₉H₂₉N₇O₆; molecular weight: 451.477) and belongs to the cysteine protease family of peptidase C1.
The product mainly appears as an almost white lyophilized powder, and can also exist in the form of white to light tan amorphous powder or liquid. It possesses specific physicochemical properties: a density of approximately 1.5±0.1 g/cm³, a flash point of 29℃, a refractive index of 1.652, solubility in water (1.2mg/mL) and glycerol, and insolubility in most organic solvents such as ethanol, chloroform, and ether. With a LogP value of -1.47, it ensures stable solubility adaptability in different application scenarios.
This product is accompanied by Chinese and US versions of Material Safety Data Sheets (MSDS) to provide comprehensive guidance on safe use. Meanwhile, it is prepared using unripe fruits of Caric papaya as raw materials, through processes including latex extraction, coagulation, sedimentation, and drying. No artificially synthesized harmful ingredients are added throughout the process, balancing natural properties with industrial practicality.
As a cysteine protease, it can accurately act on protein hydrolysis reactions. It is an enzyme associated with cathepsins in the field of metabolic enzymes/proteases, showing a clear direction of action in inflammation/immunology-related research and applications. In vitro experiments have verified its adaptability in multiple industries.
Although it is relatively sensitive to temperature, pH value, and protein denaturation factors (e.g., strong acids, alkalis, organic solvents) and prone to conformational and activity changes due to external conditions, its enzymatic activity can be stably maintained through standardized storage (airtight packaging + cool and dry environment) and control of usage conditions, making it suitable for most industrial production processes.
The acute toxicity data is clear: the oral LD₅₀ in rats is ＞4g/kg, and the oral LD₅₀ in mice reaches 12500mg/kg, ensuring high safety within the scope of reasonable use. At the same time, it indicates potential hazards to the water environment, providing clear guidance for environmentally friendly use.
Using latex from unripe papaya fruits as raw materials, it is different from chemically synthesized enzyme preparations, with no residue risk. It meets the demand for "natural ingredients" in fields such as food and cosmetics, and is especially suitable for green production systems.
It combines efficient protein hydrolysis ability with mild action characteristics. It can not only meet the needs of food ingredient modification in the food industry, but also adapt to sophisticated processes in the pharmaceutical field (e.g., dental caries removal), and be used in textile fabric treatment and cosmetic ingredient preparation, with a wide cross-industry application scope.
It has targeted enzymatic activity, enabling high catalytic efficiency with low dosage, which can reduce the amount of raw materials used by enterprises. Meanwhile, as a non-hazardous good (transportation code: NONH), it has low logistics control costs, reducing the operating pressure of the entire industrial chain.
It can be used as a meat tenderizer to decompose connective tissue proteins in meat, improving meat texture. It can also be used for dairy protein modification to enhance product delicacy, or for plant protein hydrolysis to prepare easily absorbable peptide nutritional products, balancing taste optimization and nutritional upgrading.
Relying on its mild protein decomposition ability, it can assist in chemical-mechanical caries removal in dentistry (relevant studies have verified that it can reduce damage to healthy tissues in the treatment of primary tooth caries). At the same time, it plays a role in auxiliary anti-inflammatory treatment and tissue repair processes, helping to improve the safety and effectiveness of medical operations.
Utilizing its ability to decompose protein impurities on fiber surfaces, it realizes fabric softening and cleaning, reduces the usage of chemical detergents, enhances the skin-friendliness and environmental attributes of textiles, and meets the production needs of high-end fabrics.
It can be used as a mild exfoliating ingredient to accurately decompose aged cutin on the skin surface, avoiding excessive friction damage. It can also be used in hair care products to improve the protein structure on the hair surface, enhance hair toughness, and reduce hair breakage.
