4-Aminobutyric Acid (CAS No.: 56-12-2), also known as γ-Aminobutyric Acid (GABA), is a naturally occurring non-protein amino acid presenting as white to off-white flaky or acicular crystals. As the primary inhibitory neurotransmitter in the brain of adult mammals, it features a stable molecular structure with the molecular formula C₄H₉NO₂ and a molecular weight of 103.120. Equipped with well-defined bioactive targets, it serves as a key raw material in biological research and specific application scenarios. The product is highly soluble in water but insoluble in organic solvents such as ethanol and ether, with controllable physical and chemical properties and mild storage requirements, capable of meeting the needs of multiple usage scenarios.
Specifically binds to GABAA (ionotropic receptors) and GABAB (metabotropic receptors) to exert neuromodulatory effects, acting as a specific tool substance in neuroscience research.
Melting point ranges from 195-204℃ (decomposes at 202℃), boiling point is 248.0±23.0℃ (at 760 mmHg), and density is 1.1±0.1 g/cm³, with reproducible performance parameters.
Offers two preparation routes—synthesis method (yield ≥85%) and fermentation method, ensuring controllable product purity and high batch stability.
Classified as a non-hazardous chemical with mild irritancy. It requires simple protective measures and poses low operational risks, complying with industrial and scientific research safety standards.
Focuses on neurodegenerative disease research, analysis of transmembrane transport signaling pathways, and exploration of GABA receptor-related mechanisms, serving as a core reagent in neuroscience laboratories.
Can be used as a raw material for feed additives to improve intestinal functions of weaned piglets and enhance the digestive absorption efficiency of farmed animals.
Acts as an organic synthesis intermediate for the production of downstream derivatives such as N-Boc-γ-aminobutyric acid and 4-phthalimidobutyric acid, applicable in the synthesis of pharmaceutical intermediates.
Non-hazardous goods with the transport code NONH for all modes of transport, no special dangerous goods transport qualifications required.
Provided in sealed and moisture-proof packaging to avoid moisture, exposure to sunlight, or mixing with strong oxidants during transportation.
Regular logistics transportation is acceptable. Handle with care to prevent package damage and dust leakage; no additional special protective measures are needed.
| Item | Specification |
|---------------------|--------------------------------------------|
| CAS No. | 56-12-2 |
| Molecular Formula | C₄H₉NO₂ |
| Molecular Weight | 103.120 |
| Appearance | White to off-white flaky/acicular crystals |
| Melting Point | 195-204℃ (decomposes at 202℃) |
| Solubility | Highly soluble in water; insoluble in ethanol, ether, benzene |
| Storage Conditions | Store in a cool, well-ventilated place, protected from light, sealed and dry |
| Preparation Processes | Synthesis method (pyrrolidone ring-opening hydrolysis) / Fermentation method (E. coli conversion of L-glutamic acid) |
| Safety Statements | Complies with S26 (Rinse immediately after eye contact) and S36 (Wear protective clothing) |
Q1: What is GABA (gamma-aminobutyric acid)?
A1: GABA is a naturally occurring neurotransmitter. It plays a key role in brain function, especially in calming the central nervous system. It helps reduce anxiety, improve sleep, and support mental health.
Q2: What are the benefits of GABA supplements?
A2: GABA supplements calm the brain. They help reduce anxiety, promote better sleep, and support brain metabolism. GABA also aids in treating liver disease, stroke rehabilitation, cerebral arteriosclerosis, head trauma sequelae, and coma caused by uremia or gas poisoning.
Q3: How does GABA support liver health?
A3: GABA helps lower blood ammonia levels, benefiting those with liver disease. It promotes brain metabolism and aids in treating hepatic coma, improving liver function.
Q4: What is the recommended dosage of GABA?
A4: The dosage of GABA varies depending on health conditions and product formulation. It is best to consult a healthcare provider before starting supplementation to determine the correct dosage.
Q5: Can GABA be used for stroke recovery?
A5: Yes, GABA helps in stroke recovery. It improves neurological function and addresses stroke sequelae, making it essential for rehabilitation.
4-Aminobutyric Acid (CAS No.: 56-12-2), also known as γ-Aminobutyric Acid (GABA), is a naturally occurring non-protein amino acid presenting as white to off-white flaky or acicular crystals. As the primary inhibitory neurotransmitter in the brain of adult mammals, it features a stable molecular structure with the molecular formula C₄H₉NO₂ and a molecular weight of 103.120. Equipped with well-defined bioactive targets, it serves as a key raw material in biological research and specific application scenarios. The product is highly soluble in water but insoluble in organic solvents such as ethanol and ether, with controllable physical and chemical properties and mild storage requirements, capable of meeting the needs of multiple usage scenarios.
Specifically binds to GABAA (ionotropic receptors) and GABAB (metabotropic receptors) to exert neuromodulatory effects, acting as a specific tool substance in neuroscience research.
Melting point ranges from 195-204℃ (decomposes at 202℃), boiling point is 248.0±23.0℃ (at 760 mmHg), and density is 1.1±0.1 g/cm³, with reproducible performance parameters.
Offers two preparation routes—synthesis method (yield ≥85%) and fermentation method, ensuring controllable product purity and high batch stability.
Classified as a non-hazardous chemical with mild irritancy. It requires simple protective measures and poses low operational risks, complying with industrial and scientific research safety standards.
Focuses on neurodegenerative disease research, analysis of transmembrane transport signaling pathways, and exploration of GABA receptor-related mechanisms, serving as a core reagent in neuroscience laboratories.
Can be used as a raw material for feed additives to improve intestinal functions of weaned piglets and enhance the digestive absorption efficiency of farmed animals.
Acts as an organic synthesis intermediate for the production of downstream derivatives such as N-Boc-γ-aminobutyric acid and 4-phthalimidobutyric acid, applicable in the synthesis of pharmaceutical intermediates.
Non-hazardous goods with the transport code NONH for all modes of transport, no special dangerous goods transport qualifications required.
Provided in sealed and moisture-proof packaging to avoid moisture, exposure to sunlight, or mixing with strong oxidants during transportation.
Regular logistics transportation is acceptable. Handle with care to prevent package damage and dust leakage; no additional special protective measures are needed.
| Item | Specification |
|---------------------|--------------------------------------------|
| CAS No. | 56-12-2 |
| Molecular Formula | C₄H₉NO₂ |
| Molecular Weight | 103.120 |
| Appearance | White to off-white flaky/acicular crystals |
| Melting Point | 195-204℃ (decomposes at 202℃) |
| Solubility | Highly soluble in water; insoluble in ethanol, ether, benzene |
| Storage Conditions | Store in a cool, well-ventilated place, protected from light, sealed and dry |
| Preparation Processes | Synthesis method (pyrrolidone ring-opening hydrolysis) / Fermentation method (E. coli conversion of L-glutamic acid) |
| Safety Statements | Complies with S26 (Rinse immediately after eye contact) and S36 (Wear protective clothing) |
Q1: What is GABA (gamma-aminobutyric acid)?
A1: GABA is a naturally occurring neurotransmitter. It plays a key role in brain function, especially in calming the central nervous system. It helps reduce anxiety, improve sleep, and support mental health.
Q2: What are the benefits of GABA supplements?
A2: GABA supplements calm the brain. They help reduce anxiety, promote better sleep, and support brain metabolism. GABA also aids in treating liver disease, stroke rehabilitation, cerebral arteriosclerosis, head trauma sequelae, and coma caused by uremia or gas poisoning.
Q3: How does GABA support liver health?
A3: GABA helps lower blood ammonia levels, benefiting those with liver disease. It promotes brain metabolism and aids in treating hepatic coma, improving liver function.
Q4: What is the recommended dosage of GABA?
A4: The dosage of GABA varies depending on health conditions and product formulation. It is best to consult a healthcare provider before starting supplementation to determine the correct dosage.
Q5: Can GABA be used for stroke recovery?
A5: Yes, GABA helps in stroke recovery. It improves neurological function and addresses stroke sequelae, making it essential for rehabilitation.
